Frequently Asked Questions
Please have a read of our recently asked questions!
Yes — although CBD comes from the cannabis plant family like its intoxicating cousin compound THC, you will not feel a “high” or psychoactive effect from CBD. Although there are tiny trace amounts of THC in most CBD products, the amount is so low that it is functionally impossible to get intoxicated from it. Therefore, CBD is legal to purchase and own across the United Kingdom. You can shop for CBD products with full confidence (and at E2CBD, we provide unique batch lab reports so that you can see exactly what you’re putting in your body, and in what proportion).
By all measurable results, CBD is extremely safe for humans to ingest. In fact, clinical trial data published by the journal Current Pharmaceutical Design showed that oral administration of CBD is safe even in extremely high doses. That being said, some users do report mild side effects when using CBD. CBD will affect everyone differently, and you should always consult with your physician before beginning to supplement with CBD. Even when you do begin dosing with CBD, you should start with a small dose and work your way up until you understand how CBD affects your unique physiology. Mild side effects from CBD are usually reported by users who took relatively high doses. Drowsiness or grogginess was the most common of these side effects. More than this, however, the most important consideration before taking CBD is to determine how it interacts with any drugs you are currently on. CBD may interfere with the way your drug regimen is working, so it’s critical that you have a conversation with your doctor to confirm that it’s appropriate to begin using CBD on your own.
No — CBD will not get you “high” like the other famous chemical compound found in cannabis (THC). However, just because it doesn’t give you a “body buzz” or intoxicating high does not mean that you won’t feel an effect from taking CBD. The most commonly reported effects include a general sense of well-being or anxiety reduction, or a calm clarity of focus. Regardless, there is no intoxication involved. The World Health Organization has determined that there is no potential for abuse in terms of CBD usage.
CBD affects everyone differently, but don’t go into your first CBD dose expecting to feel a “body high” or effect similar to THC-rich cannabis. It simply doesn’t work that way. THC binds directly to your CB1 and CB2 receptors; CBD, on the other hand, acts as a sneaky indirect agonist of cannabinoid receptors. That all means, in layman’s terms, that you won’t “feel” a prominent effect from taking CBD. In fact, for many CBD users, it’s more about what they don’t feel when they dose CBD. Many people report that they feel calmer, with less anxiety, more able to fall asleep, and less agitated or irritable. And of course, many people also swear by CBD’s ability to alleviate or resolve chronic pain and inflammation issues.
The CBD molecule formula is C21H30O2, with a molecular weight of 314.469 g/mol. It’s a phytocannabinoid (cannabinoid derived from a plant; specifically, the cannabis species) that is “devoid of psychoactive activity, with analgesic, anti-inflammatory, antineoplastic and chemopreventive activities (source: PubChem, National Institute of Health). As mentioned earlier, the CBD molecule is a mysterious one for several reasons. While THC binds so neatly to the CB1 and CB2 cannabinoid receptors, CBD probably does not. We do know that it stimulates endoplasmic reticulum stress and “inhibits AKT/mTOR signaling” — which means that CBD probably helps promote the normal breakdown and regeneration of dead cells, processes known as autophagy and apoptosis.
This is the million dollar question: what can CBD be used for? Before we dive into some of the uses, we need to make clear the fact that CBD research is in its infancy, and there are only a handful of definitive CBD studies right now. Therefore, it would be highly irresponsible to suggest that CBD is definitely or directly linked to any of these potential applications. Right now, CBD usage is wide open, and people are self-treating for a wide variety of symptoms. Pain and Inflammation Relief One of the most highly researched potential applications of CBD right now is its analgesic effect. It’s likely that CBD disrupts pain receptors, paradoxically triggering release of dopamine and serotonin instead. There’s evidence to suggest that this can work even in patients for whom pharmaceutical options aren’t working, or for whom it isn’t safe to prescribe them. Anxiety Relief One of the most popular reasons people purchase products on CBDfx.com, according to reviews and anecdotal user reports, is for anxiety relief. CBD has even been shown to counteract many of the effects of THC, including reduction of paranoia, stress, and anxiety. Several studies have already demonstrated measurable anxiety reduction from CBD usage based on biometric data while participants engaged in public speaking. Anti-Nausea Effect Via indirect agonism of 5-HT(1A), CBD has been shown to attenuate vomiting and nausea-related behavior according to a 2012 study. CBD indirectly activates autoreceptors in the dorsal raphe nucleus, which produces an anti-emetic (anti-nausea) effect. This can be an unspeakable relief for people who are experiencing nausea for a wide variety of reasons. Anti-Psychotic CBD is often discussed as part of a potential future treatment for schizophrenia and other forms of psychosis. The compound has been shown to induce a calming, anti-psychotic property in both humans and animals in more than one study. Skin Care Particularly when it comes to the cessation of eczema and acne, CBD oil (used as a topical treatment) is becoming increasingly popular. It’s thought that CBD’s anti-inflammatory potential could work synergistically with its positive effect on skin appearance and health. Insomnia Treatment CBD can have a sedative effect, particularly at higher doses. If you’ve ever suffered from insomnia or a condition that was keeping you from falling asleep, you know what a relief it can be to finally drift off for even a few hours.
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